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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name hsa-miR-320a
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line serum; human umbilical vein endothelial cells (HUVECs)
Methods TaqMan miRNA assay, transfection, luciferase reporter assay, ELISA
Expression pattern up-regulated
Functional description miR-320a and miR-27b are associated with new onset of retinopathy and progression of retinopathy. They may have clinical utility given their established links to angiogenesis, including the translational control of TSP-1 by miR-27b and its reduced endothelial secretion by miR-320a.
PubMed ID 26395742
Year 2016
Title Angiogenic microRNAs Linked to Incidence and Progression of Diabetic Retinopathy in Type 1 Diabetes.
Drug-related ncRNA NO

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